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Sildenafil for Prevention of Cerebral Vasospasm | Clinical Trials | Clareo Health

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WITHDRAWNPhase 2NCT01091870

Sildenafil for Prevention of Cerebral Vasospasm

A Randomized Clinical Trial with security and dose testing of Sildenafil Citrate in patients with subarachnoid hemorrhage due to a rupture of a cerebral aneurism for prevention of cerebral vasospasm. ...

Lead sponsor: Hospital de Clinicas de Porto Alegre•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Hospital de Clinicas de Porto Alegre

Age

20 - 80 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Males and females between 20 and 80 years old
•Subarachnoid hemorrhage confirmed by CT with Fisher III or IV criteria (blood in cisterns larger than 1 mm with or without blood in the ventricular system).
•Aneurysm detected in the conventional angiography, or angio-CT or angio - MRI.
•Patient underwent surgery for clipping or endovascular treatment in the first 72 hours after the ictus.
•Consent form signed by the patient or legal responsible.

Exclusion Criteria

•Patient (or legal responsible) refuses to participate.
•Impossibility to collect consent form.
•Hemodynamical instability.
•Previous cardiac ischemic disease.
•History of cardiac arrhythmia within the last 6 months.
•History of Retinitis Pigmentosa.
•Previous use of drugs witch can interact with sildenafil (specially nitrates).
•Pregnancy.
•Known hypersensibility to Sildenafil.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 25, 2015Terms

Trial snapshot

StatusWITHDRAWN

PhasePHASE2

Enrollment—

Start dateMar 2010

Last updatedMar 25, 2015

Condition

Subarachnoid Hemorrhage Cerebral Vasospasm Rupture of Intracranial Aneurysm

Locations shown

Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 25, 2015Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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