Feasibility Study of BMAC Enhanced CABG

Exclusion Criteria

• •Female who is pregnant or nursing, or of child bearing potential and is not using a reliable birth control method, or who intend to become pregnant during the tenure of this study.
• •History of Prior Radiation Exposure for oncological treatment.
• •History of Bone Marrow Disorder (especially NHL, MDS) that prohibit transplantation.
• •History of abnormal Bleeding or Clotting.
• •History of Liver Cirrhosis.
• •Acute Myocardial Infarction \< 4 weeks from treatment date.
• •Known active malignancy or results outside of normal limits from the following tests: PAP, Chest X-ray, PSA, Mammogram, Hemoccult unless follow-up studies reveal patient to be cancer free.
• •Active clinical infection being treated by antibiotics within one week of enrollment
• •Terminal renal failure with existing dependence on dialysis
• •Inability or unwillingness to comply with the treatment protocol, follow-up, research tests, or give consent.
• •Unable to have 250cc bone marrow harvested.
• •Medical risk that precludes anesthesia or ASA Class 5
• •History of ventricular arrhythmia if AICD is not present.
• •History of ventricular aneurysm.
• •Concurrent surgery such as CABG with valve surgery.
• •Minimally Invasive bypass surgery
• •Life expectancy \<6 months due to concomitant illnesses
• •Treatment with immunosuppressant drugs (including Prednisone \> 5 mg per day)
• •Patients undergoing urgent by pass surgical procedure
• •Patients with HGB A1C \> 8.5%