Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Astellas Pharma Inc
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Subject has been diagnosed with type 2 diabetes
Subject has a HbA1c value between 6.8 and 9.5%
Subject has never, is not currently taking anti-diabetic medication OR is receiving a single anti- diabetic agent or low-doses two anti-diabetic medications and is willing to discontinue them during the study
Subject is on a stable diet and exercise program
Female subject is not pregnant and agrees to use an acceptable form of contraception throughout the duration of the study
You may not be if
Subject has type 1 diabetes mellitus
Subject is using insulin therapy
Subject has a serum creatinine higher than upper limit of normal
Subject has an ALT and/or AST value higher than 3 times upper limit of normal or a total bilirubin value more than 2 times upper limit of normal
Subject has persistent, uncontrolled severe hypertension as indicated by a
systolic blood pressure \>180 mmHg or a diastolic blood pressure of
\>110mmHg
Subject has had significant cardiovascular disease such as myocardial infarction or a vascular intervention (e.g., angioplasty or stent) in the last 3 months
Subject is known to have hepatitis or be a carrier of hepatitis B surface
antigen, hepatitis C virus antibody or is known positive for HIV1 and/or
HIV2
Subject has a history of lactic acidosis
Subject has a history of drug and alcohol abuse/dependency within last 12
months
Subject has had a malignancy in the last 5 years, except for successfully
treated basal or squamous cell carcinoma of the skin or of the cervix
Subject has a symptomatic urinary tract infection or genital infection
Female subject is lactating
Subject has an unstable medical or psychiatric illness
Clareo Health | A Study to Evaluate the Effect of ASP1941 in Adult Patients With Type 2 Diabetes Mellitus
