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WITHDRAWNNANCT01067677

Rescue Emetic Therapy for Children Having Elective Surgery

To compare ondansetron, metoclopramide, diphenhydramine, and placebo in order to determine which anti-emetic is most efficacious as a "rescue therapy" for pediatric patients ages 3-18 who have post-op...

Lead sponsor: Franklyn Cladis•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Franklyn Cladis

Age

3 - 18 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Pediatric patients 3-17 years old
•2. Patients scheduled for tonsillectomy and/or adenoidectomy (with and without myringotomy) , or dental restoration,
•3. Patients receiving a general anesthetic (inhaled agent without nitrous oxide) with POV prophylaxis with two agents (ondansetron and dexamethasone)
•4. Post operative vomiting in PACU or second stage recovery requiring antiemetic rescue.

Exclusion Criteria

•1. Vomiting in the past 24 hours or antiemetics in previous 24 hours
•2. Allergy or sensitivity to ondansetron, dexamethasone, metoclopramide, or diphenhydramine
•3. Patients with diabetes
•4. Patients with seizures
•5. Patients receiving a benzodiazepine premedication

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 14, 2017Terms

Trial snapshot

StatusWITHDRAWN

PhaseNA

Enrollment—

Start dateFeb 2010

Last updatedNov 14, 2017

Condition

Post Operative Nausea and Vomiting Rescue Emetic Therapy

Locations shown

The Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 14, 2017Data synced to Clareo: May 17, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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