Lead Sponsor

Bioprojet

Age

30 - 80 years

Sex

ALL

Healthy Volunteers

No

•Patients with a documented history of Parkinson's disease according to UPDRS,fluctuator and non-fluctuator patients, Hoehn and Yahr score \<5;
•stabilized on optimal antiparkinsonian treatments unmodified for 4 weeks prior to study entry;
•presenting an Excessive Daytime Sleepiness as indicated by an ESS\>or=12

•Patients with a known diagnosis of other degenerative parkinsonian syndromes (e.g. Progressive supra-nuclear palsy, multisystemic atrophy, corticobasal degenerescence, diffuse Lewy's Body dementia)
•Patients who have shift work, chronic or occasional sleep deprivation, circadian rhythm disorders
•Patients with a severe depression indicated by (BDI\>= 16)or at suicidal risk (BDI item G\>0) or depression treated for less than 8 weeks
•Patients with a cognitive impairment