Lifestyle Intervention Trial in Obese Elderly

Exclusion Criteria

• •Any major chronic diseases
• •Any condition or unstable diseases that would interfere with exercise or dietary restriction, in which exercise or dietary restriction are contraindicated, or that would interfere with interpretation of results that include but are not limited to:
• •Cardiopulmonary disease (e.g., recent MI, unstable angina, stroke etc.)
• •Severe orthopedic/musculoskeletal or neuromuscular impairments that would contraindicate participation in exercise
• •Visual or hearing impairments that interfere with following directions
• •Diagnosis of dementia
• •History of malignancy during the past 5 yr
• •Recent use of bone acting drugs (e.g. use of estrogen, or androgen containing compound, raloxifene, calcitonin, parathyroid hormone during the past year or biphosphonates during the last two years)
• •Individuals on insulin or with a fasting blood glucose of \> 140mg/dl, and/or a 2 hour post-glucose of \>250 mg/dl
• •BMD t-scores of \<-2.3 of the lumbar spine and proximal femur
• •serum creatinine \>2.0 mg/dl
• •No commitments, life situations or conditions that would interfere with their participation in the study