Male age 18-50

Patient in good health as deemed by pre-study exam and history

BMI 20-30 kg/sq. meter

Absence of tremors

Must be willing to remain in confinement for 17 days/16 nights

Systolic BP 90-140 mmHg, diastolic BP 50-90 mmHg, resting HR 45-90 bpm

Subject must be non-smoker or willing to abstain from smoking day -4 through day 30.

Subject must abstain from alcohol, grapefruit,and caffeine-containing beverages starting Day -2 through Day 30.

Subjects must use double-barrier contraception through course of study + 90 days following study

Safety and Tolerability of LIM-0705 in Healthy Male Subjects