Inability to take or tolerate oral medication

Acute crisis or hospitalization within 1 month of enrollment

Hepatic dysfunction (SGPT greater than 3X normal)

Renal dysfunction (Creatinine greater than 2X normal)

Allergy to glutamine

Pregnancy or breastfeeding

Patients on sildenafil (Viagra), calcium channel blockers, or amino acid/protein supplements (other therapies acceptable if stable more than 3 months)

Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension

What this study is about