Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features

You may be eligible if

• DISEASE CHARACTERISTICS:
• Histologically confirmed diagnosis of 1 of the following:
• * Neuroblastoma
• * Rhabdomyosarcoma
• * Wilms tumor
• * Retinoblastoma
• * Adrenocortical carcinoma
• * Carcinoid tumor
• Relapsed or refractory disease
• Measurable or evaluable disease
• No known curative therapy or therapy proven to prolong survival with an acceptable quality of life
• No known pulmonary tumors or metastases \> 5 cm, as evaluated by chest CT scan
• No clinically significant pulmonary and/or pericardial effusions (≥ grade 3), as evaluated by ECHO
• No primary CNS tumors or known metastatic CNS disease involvement
• PATIENT CHARACTERISTICS:
• Karnofsky performance status (PS) 50-100% (for patients \> 16 years of age)
• Lansky PS 50-100% (for patients ≤ 16 years of age)
• Peripheral ANC ≥ 1,000/mm\^3
• Platelet count ≥ 100,000/mm\^3 (transfusion independent, defined as no platelet transfusions within a 7-day period before study enrollment)
• Hemoglobin ≥ 8.0 g/dL (RBC transfusions allowed)
• Creatine clearance or radioisotope GFR ≥ 70 mL/min OR serum creatinine based on age/gender as follows:
• * ≤ 0.8 mg/dL (for patients 3 to 5 years of age)
• * ≤ 1.0 mg/dL (for patients 6 to 9 years of age)
• * ≤ 1.2 mg/dL (for patients 10 to 12 years of age)
• * ≤ 1.4 mg/dL (for female patients ≥ 13 years of age)
• * ≤ 1.5 mg/dL (for male patients 13 to 15 years of age)
• * ≤ 1.7 mg/dL (for male patients ≥ 16 years of age)
• Bilirubin (sum of conjugated and unconjugated) ≤ 1.5 times upper limit of normal (ULN)
• SGPT ≤ 110 U/L (for the purpose of this study, the ULN for SGPT is 45 U/L)
• Serum albumin ≥ 2 g/dL
• Oxygen saturation \> 92% on room air
• Not pregnant or nursing
• Negative pregnancy test
• Fertile patients must use effective contraception
• Able to comply with the safety monitoring requirements of the study, in the opinion of the investigator
• Completely toilet trained
• No chronic diarrhea or urinary incontinence during the day or night, , and no in-dwellling urinary catheters
• No uncontrolled infection
• No known pregnant member of the household
• PRIOR CONCURRENT THERAPY:
• Fully recovered from the acute toxic effects of all prior anti-cancer chemotherapy
• At least 6 months since prior total-body irradiation (TBI), craniospinal radiotherapy, or radiotherapy to ≥ 50% of the pelvis
• At least 3 months since prior stem cell transplantation or rescue (without TBI)
• * No evidence of active graft-vs-host disease
• At least 6 weeks since other prior substantial bone marrow radiotherapy or treatment with therapeutic doses of MIBG
• More than 3 weeks since prior myelosuppressive chemotherapy
• At least 2 weeks since prior local palliative radiotherapy (small port)
• More than 7 days since prior growth factor(s) that support platelet or white blood cell number or function
• At least 7 days since prior biologic agents
• At least 3 half-lives since prior monoclonal antibodies
• More than 7 days since prior viral immunizations, including influenza
• At least 42 days since the completion of any type of immunotherapy, e.g., tumor vaccines
• No other viral immunizations after enrolling on study until 28 days after their last planned Seneca Valley virus-001 infusion or until documented viral clearance, whichever is longest
• Concurrent corticosteroids allowed provided the patient has been on a stable or decreasing dose for the past 7 days
• No other concurrent investigational drugs
• No other concurrent anticancer agents (e.g., chemotherapy, radiotherapy, immunotherapy, or biologic therapy)
• Prior treatment with Seneca Valley virus-001 is not allowed