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Prospective casecontrol study in glioma patients undergoing treatment with bevacizumab (Avastin). At present there are no data on the correlation between occurrence of arterial hypertension and clinical outcome in patients with glioma or anaplastic astrocytoma. We will investigate whether glioma patients developing hypertension under bevacizumab treatment have a better outcome in terms of progression free survival, response rate and overall survival than equally treated patients remaining normotensive. Moreover, we will describe the dynamics of change in blood pressure after administration of bevacizumab in those patients developing hypertension. * Trial with medicinal product
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
University Hospital Zurich, Internal Medicine
Zurich, Canton of Zurich, Switzerland
Start Date
January 1, 2010
Primary Completion Date
August 1, 2012
Completion Date
August 1, 2012
Last Updated
June 13, 2013
40
ACTUAL participants
Bevacizumab
DRUG
Lead Sponsor
University of Zurich
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