Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Fundació Sant Joan de Déu
Age
40–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of schizophrenia (DSM-IV criteria)
Postmenopausal patients. Postmenopause is defined as after a period of one year of spontaneous amenorrhea and a serum follicle stimulating hormone (FSH) level \> 20IU/L.
Stable doses of their current antipsychotic medication for at least a month prior to study initiation.
Presence of significant negative symptoms (defined as one or more negative symptom score greater than 4 in the PANSS scale) (Kay 1987)
Patients have to give written informed consent to participate in the study.
You may not be if
Patients with a substance abuse/dependence diagnosis in the previous six months.
Mental retardation.
Endocrine abnormalities, acute or chronic liver disease, impaired kidney function.
History of thromboembolism, breast cancer, abnormal uterine bleeding, history of cerebrovascular accident.
Patients taking hormone replacement therapy.
Patients taking mood stabilizer medication that cannot be discontinued.
Clareo Health | Double Blind, Placebo-controlled Study of Raloxifene for Negative Symptoms of Schizophrenia in Postmenopausal Women
