Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Merck Sharp & Dohme LLC
Age
18–55
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Part 1:
Nonsmoker for at least 6 months
Body Mass Index (BMI) less than or equal to 29 kg/m2
In overall good health
Part 2:
Body Mass Index (BMI) greater than 18kg/m2 and less than or equal to 35kg/m2
In overall good health (patients with hypertension and/or hyperlipidemia are accepted)
You may not be if
Part 1:
History of any cardiovascular disease or any clinically significant family history of cardiac arrhythmias or conduction abnormalities at an age less than 60 years
History of any major endocrine, vascular, hematologic, gastrointestinal, hepatic, renal or genitourinary disease/disorder
History of cancer
Clinically significant history of a neurological disorder (includes epilepsy,stroke, transient ischemic attack, classic migraines)
Active or history of a psychiatric disorder (includes depression, bipolar disorder, schizophrenia, anxiety)
History of asthma, severe wheezing, COPD, or other pulmonary disease
Individual or family history of bleeding or hemorrhagic diathesis, or bleeding difficulties
Major surgery, donated blood or participated in another investigational drug(s) trial within 30 days
Illicit drug use (including recreational); or history of drug or alcohol abuse (within 2 years)
Nitrate therapy within 4 weeks
History of significant drug allergy or history of food allergies
Part 2
History of any clinically significant cardiac or cardiovascular disease (other than hypertension)
History of any major endocrine, vascular, hematologic, gastrointestinal, hepatic, renal or genitourinary disease/disorder
History of cancer
History of a neurological disorder (includes epilepsy,stroke, transient ischemic attack, classic migraines)
Active or history of a psychiatric disorder (includes depression, bipolar disorder, schizophrenia, anxiety)
History of asthma, severe wheezing, COPD, or other pulmonary disease
Individual or family history of bleeding or hemorrhagic diathesis, or bleeding difficulties
Illicit drug use (including recreational); or history of drug or alcohol abuse (within 2 years)
Surgery, significant blood loss, donated blood, or participated in another investigational drug(s) trial within 30 days
