Finding studies
Finding studies
Take this into the appointment.
Saves the questions and what to expect into your notes, next to the visit they belong to.
Lead
Children's Hospital Los Angeles
With
Nitric oxide (NO) is a naturally occuring chemical that relaxes blood vessels and helps improve blood flow. The pain associated with vaso-occlusive crisis (pain crisis) in sickle cell disease is caused in part by lack of oxygen and increased tissue acid because blood flow is blocked by stiff sickle red cells. Administration of sodium nitrite should generate nitric oxide in this area of hypoxia and acidosis and improve blood flow.
Age
8–23
Sex
ALL
Healthy volunteers
Not accepted