Clinical Trial of Donepezil Between the Naive Group and the Switching Group

Exclusion Criteria

• •1. they had evidence of any neurodegenerative diseases other than AD (i.e. Parkinson's disease, Huntington's disease)
• •2. Psychiatric disorder or severe behavioral disturbances that required psychotropic medications
• •3. Cerebral injuries induced by trauma, hypoxia, and/or ischemia
• •4. Clinically active cerebrovascular disease; History of seizure disorder
• •5. Other physical conditions that required acute treatment.