Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear

Inclusion Criteria

• •At least 18 years of age.
• •Understand your rights as a research subject and give written informed consent by signing the Informed Consent Form, Subject Bill of Rights, and Patient Authorization for Use and Release of Health and Research Study Information (HIPAA form).
• •Be likely to finish the entire study, understand the study instructions, and be willing to follow the instructions.
• •Contact lens prescription between +4.00 D to -9.00 D (spherical equivalent).
• •Best correctable visual acuity of at least 20/40 in each eye.
• •Willing to de-adapt (do not wear) from habitual contact lenses for a period of at least two days prior to eligibility visit and at least two days prior to the testing day.
• •Possess a functional spectacle (eyeglass) prescription to allow adequate vision during the de-adaptation and barrier function determination periods.
• •No known allergies, which may interfere with contact lens wear.
• •No known systemic (pertaining to general health) disease, or need for medication that may interfere with contact lens wear (i.e. antihistamines, beta-blockers, steroids).