NHL histological diagnosis of diffuse large B cell CD20 + (de novo or shift from low-grade NHL if not pretreated), grade IIIb follicular NHL;
Age \>= 18 years;
Presence of at least 1 factor that defines the cardiopathy;
Life expectancy \> 3 months;
In the case of women of childbearing age absence of pregnancy at the beginning of the chemotherapy;
Written informed consent.
You may not be if
Histology different from NHL diffuse large cell CD20 + or follicular IIIb
Age \< 18 years
Inability to sign informed consent;
HIV positivity;
Patients HBsAg positive;
AST/ALT \> 2 times the standard;
Bilirubin \> 2 times the standard;
Creatinine \> 2.5 mg / dl;
Location of CNS disease;
Pregnancy ongoing;
Damage to that organ or medical problems that could interfere with the therapy;
Current uncontrolled infection;
Senile dementia
Clareo Health | Study With Rituximab, Cyclophosphamide, Doxorubicin Liposomal (Myocet®), Vincristine, Prednisone, (R-COMP) to Treat Non-Hodgkin's Lymphoma