Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Carelon Research
With
National Heart, Lung, and Blood Institute (NHLBI)
Age
12–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
\>= 12 years old
\>= 40 kg body weight
Scheduled complex cardiac surgery with planned use of median sternotomy.
Patients ≥ 18 years must have a Transfusion Risk Understanding Scoring Tool (TRUST) probability score ≥ 3
You may not be if
Refusal of blood products
Planned surgery is minimally invasive
Known transfusion reaction history
Requirement for washed products, volume reduced products, or products with additive solution removed
Expected residual cyanosis with O2 saturation \< 90
Left ventricular assist device (LVAD) or Extracorporeal membrane oxygenation (ECMO) support pre-operatively or planned need post-operatively
Cardiogenic shock requiring pre-operative placement of an Intra-aortic balloon pump (IABP) (IABP done for unstable angina or prophylactically for low ejection fraction is not excluded)
Planned Deep Hypothermic Circulatory Arrest (DHCA)
Renal dysfunction requiring pre-operative renal replacement therapies such as hemodialysis (HD) or continuous venovenous hemofiltration (CVVH)
Planned use of alternative to heparin, e.g. bivalirudin
Planned use of autologous or directed donations
Prior RBC transfusion during hospitalization for the study-qualifying surgery
