Lead Sponsor

Merck Sharp & Dohme LLC

Age

18 - 45 years

Sex

ALL

Healthy Volunteers

Yes

•Subject is neither grossly overweight nor underweight for his/her height and body build
•Subject is in good health -Subject is a nonsmoker
•Subject is willing to avoid excessive alcohol consumption for the duration of the study
•Subject is willing to avoid strenuous physical activity (i.e. unaccustomed weight lifting, running, bicycling) for the duration of the study
•Subject agrees to refrain from consumption of grapefruit (and grapefruit products) before and during the study

•Subject has a history of multiple and/or severe allergies to drugs or food
•Subject has donated blood or taken an investigational drug in another clinical trial within the last 4 weeks
•Subject has an infection, including Human immunodeficiency virus (HIV) infection
•Subject is a regular user of any illicit drug
•Subject consumes excessive amounts of alcohol
•Subject drinks excessive amounts of coffee, tea, cola or other caffeinated beverages
•Subject currently uses on a regular basis, any prescription or non prescription medications

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