Active disease (≥ 5 active joints, ≥ 3 with limitation of motion).
Inadequate response to or inability to tolerate methotrexate.
Methotrexate, oral corticosteroids, and non-steroidal anti-inflammatory drugs (NSAID) at stable dose(at least 8, 4, and 2 weeks,respectively) prior to baseline.
Biologics discontinued, between at least 1 and 20 weeks prior to baseline, depending on biologic.
You may not be if
Auto-immune, rheumatic disease or overlap syndrome other than pcJIA.
Wheelchair bound or bedridden.
Intra-articular, intramuscular, intravenous, or long-acting corticosteroids within 4 weeks prior to baseline.
Disease-modifying anti-rheumatic drugs (DMARD) (other than methotrexate) within 4 weeks prior to baseline.
Previous treatment with tocilizumab.
Clareo Health | A Study of Tocilizumab in Patients With Active Polyarticular Juvenile Idiopathic Arthritis
