Lead Sponsor

Merck Sharp & Dohme LLC

Age

1 - 1 years

Sex

ALL

Healthy Volunteers

Yes

•In good health
•Negative clinical history of varicella, zoster, measles, mumps, rubella, diptheria, tetanus, pertussis, invasive Hib disease and hepatitis B
•Had completed either a 2-dose primary series of PedvaxHIB or COMVAX or any 3-dose primary series of a licensed Hib vaccine
•Had received 2 or 3 doses of any hepatitis B vaccine or COMVAX prior to entry into trial

•Previous receipt of measles, mumps, rubella or varicella vaccine either alone or in combination
•Any immune impairment or deficiency
•Recent household, daycare or school exposure to invasive Hib disease or hepatitis B
•Exposure to measles, mumps, rubella, varicella, or zoster in the 4 weeks prior to vaccination
•Vaccination with an inactive vaccine with in the past 14 days
•Vaccination with a live vaccine within the past 30 days
•Receipt of immune globulin, blood transfusion or blood-derived product in the past 3 months
•Recent history of fever or underlying medical problems