Use of any other antidiabetic drug than insulin within the last 3 months

Cardiovascular disease within the last 6 months

Uncontrolled treated/untreated severe hypertension

Recurrent severe hypoglycemia or hypoglycemic unawareness or hospitalisation for diabetic ketoacidosis during the previous 6 months

Pregnancy, breast-feeding, the intention of becoming pregnant or not using adequate contraceptive measures according to local requirements

Cancer and medical history of cancer

Comparison of NN1250 Plus Insulin Aspart With Insulin Glargine Plus Insulin Aspart in Type 1 Diabetes