Effects of 3 Months of Selective Serotonin Reuptake Inhibitor (SSRI)-Treatment on Metabolism and Hypothalamic-pituitary-adrenal (HPA)-Axis in Young Men Born With Low Birth Weight

Exclusion Criteria

• •1. Diabetes, insulin-resistance or precursors in first degree relatives or maternal gestational diabetes.
• •2. Small parents(mother \<160cm and/or father \<170cm).
• •3. History of abuse of alcohol, medicine og drugs in the mother during pregnancy.
• •4. Liver of renal failure : s-ALAT \> 2.5 normal upper limit (\>175μM) or s-creatinine \>125 μmol/l.
• •5. Co-morbidity that after at medical examination is considered to be a problem.
• •6. BMI\>25.5
• •7. Smoking that is considered to be an issue as regards completing the study.
• •8. Treatment with a MAO-inhibitor.
• •9. Born before gestational week 38.
• •10. Participation in larger X-ray examinations such CT-scans during the last 12 months.
• •11. Participation in medical experiments or treatments involving intravenous administration of radioactive substances during the last
• •12. Ongoing medical treatment that will be considered a issue for completing the study.
• •13. Allergy towards the substance Escitalopram.
• •14. Metal parts in the body that contra-indicates MRI.
• •15. Ongoing medical treatment thrombocyte inhibiting substances such as NSAIDS.
• •16. Previous gastrointestinal bleeding or gastro-duodenal ulcers.
• •17. Depression during examination or treatment
• •16/05-2011: Criterias updated - added 17 and adjusted 6. from BMI \>25 to BMI \>25.5