Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Infinity Pharmaceuticals, Inc.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
At least 18 years of age at the time of signing informed consent.
Histologic diagnosis of dedifferentiated liposarcoma.
Available archival pathology specimen or tissue sample from a new biopsy for confirmation of diagnosis by central pathology reading.
At least one prior chemotherapy regimen for dedifferentiated liposarcoma.
No more than 2 prior chemotherapy regimens for dedifferentiated liposarcoma. Note: Any number of non-chemotherapy regimens is permitted.
Measurable disease on computed tomography (CT) or magnetic resonance imaging (MRI) as defined by RECIST (version 1.1) with at least one measurable lesion.
Eastern Cooperative Oncology Group (ECOG) performance status: 0 or 1.
Life expectancy ≥6 months.
You may not be if
Prior treatment with any heat shock protein 90 (Hsp90) inhibitor.
Surgery, radiotherapy, or lesion ablative procedure to the only area of measurable disease
Patients with prior hepatic resections or hepatic-directed therapy
Use of a medication or food that is a clinically relevant CYP3A inhibitor or inducer within 2 weeks prior to dosing.
