OBJECTIVES:
Primary
* To better understand the pathophysiology of gliomas and identify molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches.
Secondary
* To compare gene expression profiles, in terms of response to treatment, and attempt to isolate subgroups of patients with objective response to certain types of chemotherapy or radiotherapy.
OUTLINE: This is a multicenter study.
Biological samples are collected from patients at time of surgery for diagnostic and/or treatment purposes.