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Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CT

NCT00958815·1 site·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Lead

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Age

35–60

Sex

ALL

Healthy volunteers

Accepted

You may be eligible if

confirmed HIV+ status
35-60 years old
stable ART for at least the past 4 mos
CD4 count \>200 cells/µL
HIV RNA \<40copies/mL
fasting glucose=100-126 mg/dL
2hr-oGTT glucose=140-200mg/dL
fasting triglycerides \>150mg/dL
HDL-cholesterol \<40mg/dL (men), \<50mg/dL (women)
resting blood pressure\>130/85mmHg
waist circumference \>102cm(men), \>88cm(women)
BMI 25-35 kg/m2
For HIV-negative control group:
Confirmed HIV negative status
35-60 years old
fasting glucose\<100mg/dL,
2hr-oGTT glucose\<140mg/dL
fasting triglycerides\<150mg/dL
HDL-cholesterol \>40mg/dL (men), \>50mg/dL(women)
normal BP (\<130/85mmHg)
no central adiposity (waist circ.\<102cm(men), \<88cm(women)
BMI (25-35 kg/m2)

You may not be if

history of heart disease, MI, stroke, transient ischemic attack, kidney or liver disease (active hepatitis B or C), dementia
statins, fibrates, TZDs, antihypertensives, low dose aspirin, or other prescribed/over-the-counter agents with anti-inflammatory properties
cocaine and methamphetamine users
serum creatinine \>1.5 mg/dL
pregnant women
cognitive impairment that limits ability to provide voluntary informed consent

The record

StatusCompleted

PhaseNo phase

Taking part14

StartedMar 2009

UpdatedJun 26, 2012

Conditions

Insulin Resistance Atherosclerosis Cardiovascular Disease HIV/AIDS HIV Infections

Where1

Washington University School of Medicine
St Louis, Missouri, United States

Clareo Health | Human Atherosclerotic Plaque Inflammation Imaged Using PDG-PET/CT