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Lead
Jonsson Comprehensive Cancer Center
OBJECTIVES:
* To determine whether the anal cytology screening outcome derived from specimens collected by a flocked nylon swab are equivalent to those derived from Dacron swab specimens in men who have sex with men.
* To determine whether the number and type-specific identification for human papillomavirus derived from specimens collected by a flocked nylon swab are equivalent to those derived from Dacron swab specimens.
OUTLINE: Dry sterile Dacron swabs and flocked nylon swabs are used to collect intra-anal cytology specimens for anal Pap testing and human papillomavirus typing. Participants undergo a digital rectal examination and high-resolution anoscopy. If lesions are identified, an anal biopsy is performed for histological examination.
Age
18–any
Sex
MALE
Healthy volunteers
Accepted
You may be eligible if
HIV-infected or -uninfected adult men who have sex with men
Concurrent enrollment in the Multicenter AIDS Cohort Study required
You may not be if
history of anal perforation or other medical contraindications