Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Amgen
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Active RA for least 6 months
Current RA defined as ≥ 6 swollen joints (out of 66 joints examined) and ≥ 8 tender/painful joints (out of 68 joints examined) at screening and baseline (swollen and tender/painful joint count must not include distal interphalangeal joints) and at least 1 of the following at screening: Erythrocyte sedimentation rate ≥ 28 mm or C-reactive protein \> 15 mg/L
At least 1 of the following at screening: Rheumatoid factor positive or Anti-cyclic citrullinated peptide antibody positive
Currently taking methotrexate for ≥ 12 weeks and on a stable dose of methotrexate at 15 to 25 mg weekly for ≥ 4 weeks at day -1.
You may not be if
Prosthetic joint infection within 5 years of screening or native joint infection within 1 year of screening
Class IV RA
Felty's syndrome
Presence of serious infection
Significant concurrent medical conditions
Pregnant or breast feeding
Significant Laboratory abnormalities
Any disease-modifying anti-rheumatic drug (DMARD) other than methotrexate within 28 days
Leflunomide or live vaccines within 3 months
Previous use of any experimental or commercially available biologic DMARD
