Japanese Bridging Study Conducted in the United States

Exclusion Criteria

• •Any significant acute or chronic medical illness.
• •Women who are pregnant, breastfeeding, or unwilling or unable to use an acceptable method of birth control.
• •Gastrointestinal disease that may impact the absorption of study drug or that required treatment with a protocon inhibitor, antacid or H2 blocker.
• •History of eczema, psoriasis, or any intermittent or active dermatitis.
• •Positive for HIV or HCV