Hormonal Effects on Tc-99m Sestamibi Uptake in the Breast

Exclusion Criteria

• •currently using any exogenous hormones (e.g., hormonal contraceptives, sex steroid hormones) or any estrogen receptor modulating drugs (e.g., tamoxifen, raloxifene) or any aromatase inhibitors
• •have a personal history of any cancer, except non-melanomatous skin cancer
• •unable to understand and sign the consent form
• •pregnant or lactating
• •physically unable to sit upright and still for 30 minutes
• •Arm 2
• •have a personal history of any cancer, except non-melanomatous skin cancer
• •unable to understand and sign the consent form
• •pregnant or lactating
• •physically unable to sit upright and still for 30 minutes
• •Arm 3
• •are using or have used any exogenous hormones (e.g., hormonal contraceptives, sex steroid hormones), any estrogen receptor modulating drugs other than tamoxifen, or any aromatase inhibitors from the time of 1 month prior to the first MBI until completion of the second MBI.
• •have been treated or will be undergoing treatment with systemic chemotherapy or external radiation beam therapy to the breast from the time of 6 months prior to the first MBI until the completion of the second MBI.
• •unable to understand and sign the consent form
• •pregnant or lactating
• •physically unable to sit upright and still for 30 minutes