Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
MediQuest Therapeutics
Raynaud's Phenomenon is a sometimes debilitating condition in which blood flow to the fingers or toes is compromised when a patient is exposed to cold or stress. Current therapies for Raynaud's are suboptimal because they are associated with significant side effects. In this study, patient responses to cold temperature exposures in a climate-controlled room after application of the study medication are measured.
Age
18–70
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
clinical diagnosis of Raynaud's phenomenon as determined by a history of cold sensitivity with pain, numbness, and/or tingling along with pallor or cyanosis of the fingers
a history of at least two Raynaud's events during a typical winter day
must be willing to apply creams to fingers
must be willing to undergo cold temperature exposure
must be willing and able to stop certain medications
must be willing to use effective contraception, if applicable
You may not be if
had a Raynaud's attack that required hospital or clinic intervention
has allergies to nitroglycerin or topical medication ingredients
has a history of migraine or chronic pain
has an unstable medical problem that could interfere with the study
had a heart attack or uncontrolled heart problems, hypertension, or hypotension in the past 3 months
used any investigational drug in the past 4 weeks
has significantly abnormal laboratory tests
had certain major surgeries in the past 6 months
has skin lesions on certain parts of the fingers
women who are pregnant or nursing
Clareo Health | Study of a Topical Formulation for the Treatment and Prevention of Raynaud's Phenomenon Symptoms
