Characterisation of 24-hour FEV1-time Profiles of Inhaled BI 1744 CL and Inhaled Foradil in Patients With Chronic Obstructive Pulmonary Disease

Exclusion Criteria

• •Significant other disease
• •clinically relevant abnormal hematology, chemistry, or urinalysis
• •history of asthma
• •diagnosis of thyrotoxicosis
• •paroxysmal tachycardia related to beta agonists
• •history of MI within 1 year, cardiac arrhythmia, hospitalization for heart failure within 1 year
• •active tuberculosis, cystic fibrosis, clinically evident bronchiectasis
• •significant alcohol or drug use
• •pulmonary resection
• •taking oral beta adrenergics
• •taking unstable oral steroids
• •daytime oxygen
• •enrolled in rehabilitation program
• •enrolled in another study or taking investigational products
• •pregnant or nursing women, women of child bearing potential not willing to use two methods of birth control
• •those who are not willing to comply with pulmonary medication washouts