Duloxetine Versus Pregabalin for Alcohol Dependence

Exclusion Criteria

• •Active suicidal ideation
• •Medical disorders that will increase potential risk or interfere with study participation
• •Sexually active female subjects with childbearing potential who are pregnant, nursing or refuse to use a reliable method of birth control
• •Males who refuse to use a reliable method of birth control
• •Meets DSM-IV criteria for any other current major AXIS I disorder other than alcohol or nicotine dependence.
• •Inability to understand and/or comply with the provisions of the protocol and consent form
• •Treatment with an antidepressant medication during the two weeks, or fluoxetine during the month, prior to randomization
• •Ongoing treatment with disulfiram (Antabuse), naltrexone (ReVia), acamprosate (Campral) or other medications that may affect study outcomes, e.g., anticonvulsants or other drugs that act on serotonin in the brain
• •Ongoing treatment with drugs that may increase potential risk (Actos),