confirmed first diagnosis of or relapsed CD20-positive Immunocytoma, B-CLL or other indolent B-NHL
therapy-requiring CLL defined as: Binet stage C or Binet B combined with occurence of B-symptoms, rapidly progressing disease, risk of organ compression by lymphoma mass
therapy-requiring Immunocytoma as defined by the Consensus Panel Recommendations from the Second International Workshop on Waldenström´s Macroglobulinemia, 2003)
age \> 18 years
anticipated life expectancy \> 6 months
ECOG 0-3
no significant comorbidities
signed informed consent
efficient method of contraception during time of therapy (men and women)
You may not be if
age \< 18 years
CD20 negativity
significant comorbidities interfering with therapy as required by the protocol
