pregnant or lactating females

previous treatment for breast cancer

other tumor history

instable complication (e.g., myocardial infarction within 6 months, arrhythmia, unstable diabetes, hypercalcemia) or uncontrolled infection

allergy history to similar drugs

concurrent disease or condition that would make the patient inappropriate for study participation

resist to participate in the study

Comparison of Neo-adjuvant Weekly Paclitaxel With or Without Carboplatin in Early Breast Cancer