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A Randomised Double Blind Controlled Trial Comparing Ciclosporin and Prednisolone in the Treatment of New Leprosy Type 1 Reactions
Study 1A: Ciclosporin in the management of new Type 1 Reactions in Leprosy Objective: A randomised double blind controlled trial comparing Ciclosporin and Prednisolone,to determine whether treatment with Ciclosporin gives the same outcome in the treatment of new Type 1 Reactions as Prednisolone.
We tested our hypothesis that ciclosporin would be as effective as prednisolone in the treatment of patients with leprosy reactions and nerve function impairment and that patients treated with ciclosporin would have fewer side effects than patients treated with prednisolone. A randomised controlled trial comparing ciclosporin and prednisolone in the treatment of acute leprosy T1R was conducted.
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
Alert Hospital
Addis Ababa, Ethiopia
Start Date
August 1, 2010
Primary Completion Date
December 1, 2012
Completion Date
July 1, 2013
Last Updated
March 24, 2015
73
ACTUAL participants
Ciclosporin
DRUG
Prednisolone
DRUG
Lead Sponsor
London School of Hygiene and Tropical Medicine
Collaborators
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06819449