Vascular Reactivity in Chronic Kidney Disease (CKD) Patients Receiving Paricalcitol Versus Placebo

Exclusion Criteria

• •History of any of the following diseases:
• •* congestive heart failure
• •* MI within the last 6 months
• •* history of cerebrovascular accident
• •* significant valvular disease
• •* malignancy
• •Currently taking any vitamin D products
• •Mean systolic blood pressure values \> 190 or diastolic blood pressure values \> 100 mm/Hg during the preceding 30 day period prior to screening
• •Currently being titrated on therapy with an angiotensin converting enzyme inhibitor or angiotensin receptor blocker
• •Two consecutive serum calcium values greater than 10.2 mg/dL or Ca x P \> 55 mg2/dL2
• •Currently receiving erythropoiesis stimulating agent or intravenous iron therapy
• •Pregnant or breastfeeding