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Berlin Magnetic Seizure Therapy Depression Trial 01 | Clinical Trials | Clareo Health

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Berlin Magnetic Seizure Therapy Depression Trial 01

Investigation of Efficacy and Tolerability of Magnetic Seizure Therapy in the Treatment of Depression

NCT00914680•Charite University, Berlin, Germany

Summary

This treatment pilot study will investigate clinical efficacy and adverse effects of magnetic seizure therapy (MST) in patients currently experiencing a unipolar or bipolar depressive episode. The investigators will perform add-on tests to assess clinical and cognitive response to treatment. It is hypothesized that MST will have an antidepressant efficacy with a beneficial neurocognitive adverse effect profile.

Eligibility

Age

25 - 80 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patient is diagnosed with a severe major depressive episode
•Patient is in a chronic current MDE and/or has had a history of recurrent MDEs
•Patient has not had an acceptable clinical response due to failure with at least 2 antidepressant treatments during the current episode
•Patient has a score \> 20 on the HAMD24
•Patient is stable on current psychotropic medication for at least 4 weeks
•Patient is \> 25 and \< 80 years

Exclusion Criteria

•Atypical Depression or psychotic depression (according to DSM IV)
•Other relevant psychiatric axis I or axis II diseases
•Relevant neurological diseases
•Relevant cardiac or pulmonary diseases with enhances anesthesiological risk (ASA Score \> 3)
•Patient is currently enrolled in another investigational study not associated with the current study
•Patient has a history of, or evidence of, significant brain malformation or significant head injury

Locations (1)

Department of Psychiatry, CC15, CBF, Eschenallee 3

Berlin, Germany

Key Dates

Start Date

June 1, 2009

Primary Completion Date

May 1, 2012

Completion Date

May 1, 2013

Last Updated

July 13, 2018

Enrollment

ESTIMATED participants

Conditions

Unipolar DepressionBipolar Depression

Interventions

magnetic seizure therapy

PROCEDURE

University of Iowa Interventional Psychiatry Service Patient Registry

NCT04480918

Treatment Resistant DepressionMajor Depressive Episode+5 more

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RECRUITINGNA

Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression

NCT06524505

Bipolar Depression

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 13, 2018Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Berlin Magnetic Seizure Therapy Depression Trial 01

Inclusion Criteria

Exclusion Criteria

University of Iowa Interventional Psychiatry Service Patient Registry

Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression

A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)

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HD-tDCS for Adolescent Bipolar Depression Targeting S1

Transcranial Direct Current Stimulation for Depression