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Behavioral Treatment for Cocaine Dependent Women | Clinical Trials | Clareo Health

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COMPLETEDPhase 2NCT00914381

Behavioral Treatment for Cocaine Dependent Women

To compare the efficacy of Community Reinforcement Approach (CRA) and 12-Step Facilitation (TSF) counseling and of voucher based reward therapy (VBRT) and a yoked, non-contingent voucher control (VC) ...

Lead sponsor: Yale University•2 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Yale University

Collaborators

National Institute on Drug Abuse (NIDA)

Subjects were randomly assigned to 1 of 4 treatment groups (CRA+VBRT, CRA+VC, TSF+VBRT, TSF+VC). VBRT voucher value increased for each successive cocaine-free urine sample obtained twice weekly during the 1st 12 weeks and was faded from the final earned value to $5 during the last 12 weeks. All subjects earned vouchers for attendance at scheduled twice weekly counseling sessions. Manual-guided CRA and TSF were provided by experienced clinicians.

Age

18 - 50 years

Sex

FEMALE

Healthy Volunteers

No

Inclusion Criteria

•Pregnant women meeting DSM IV criteria for cocaine dependence
•Women meeting DSM IV criteria for cocaine dependence with custody of a young child

Exclusion Criteria

•Opioid dependence
•Psychosis
•Severe depression
•Current treatment with any anti-depressant or anti-psychotic medication
•Medical instability
•Inability to understand or read English

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 31, 2020Terms

Trial snapshot

StatusCOMPLETED

PhasePHASE2

Enrollment145

Start dateDec 1994

Last updatedMar 31, 2020

Condition

Cocaine Dependence

Locations shown

The APT Foundation, Inc. MRU

New Haven, Connecticut

Yale University School of Medicine

New Haven, Connecticut

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 31, 2020Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions