Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Wellspect HealthCare
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Provision of informed consent
Male and female patients aged 18 years and over
MS patients that are already currently treated or eligible for treatment with anticholinergic drugs
Patient with previously confirmed multiple sclerosis according to McDonald Criteria and level of disability less than 6.5 on the Kutzke scale and have been stable for 6 months
The patient has all or any bladder symptoms; urgency, frequency, incontinence, nocturia, PVR
The patient has Frequency symptoms \> 8 voiding per 24 h
The patient has PVR \> 50 ml, measured at two repetitive bladder scan measurements during the screening phase as well as the randomization visit
Adequate mobility to lower limbs, sufficient hand function and ability to practice CIC at least three times daily
You may not be if
Pregnancy
Ongoing symptomatic Urinary Tract Infection (UTI) as judged by investigator
Involvement in the planning and conduct of the study (applies to both Astra Tech staff or staff at the study site)
The patient practices CIC prior the study
The patient has undergone a sphincterectomy
Progressive "Relapsing- remitting MS" as judged by the investigator
Severe non-compliance to protocol as judged by the investigator and/or Astra Tech
The patient is participating in other study that might have an impact on the outcome of this, as judged by investigator
PVR \> 250 ml, measured at two repetitive bladder scan measurements during the screening phase as well as the randomization visit and or if Bladder Voiding Efficiency (BVE) at visit 2 (randomization) is 50% or less than visit 1 (screening)
