Feasibility Study to Determine the Effects of Phrenic Nerve Stimulation in Patients With Periodic Breathing

Exclusion Criteria

• •Baseline oxygen saturation less than or equal to 90% on a stable FIO2
• •Evidence of phrenic nerve palsy
• •Temperature \> 38.0 degrees Celsius
• •Inability to place catheter (e.g. previously known coagulopathy, distorted anatomy, etc.)
• •Patient is currently enrolled in another study that may confound the results of this study
• •Patient for whom informed consent cannot be obtained
• •Patient who is pregnant or of child bearing potential without a negative pregnancy test within 10 days of the study procedure
• •Patients implanted with a pacemaker, implantable defibrillator, or cardiac resynchronization device who are unable to tolerate turning off the device for the duration of the system testing procedure (based on medical judgment)
• •Patients with severe COPD (per GOLD scale)
• •Patients with a history of myocardial infarction within 6 months prior to the study
• •Patients with unstable angina
• •Patients who are intolerant of or allergic to contrast dye
• •Patients who are contraindicated for \<1mg of steroid (on the stimulation lead).