Clareo Health | Endothelial Function, Inflammatory Disease Activity, and Bone and Cartilage Markers in Rheumatic Patients: The Influence of Antirheumatic Treatment
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Revmatismesykehuset AS
With
Abbott
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Males and females 18-80 years
Able and willing to give written informed consent, and to comply with the requirements of the study protocol.
Fulfilling the ACR 1987 revised diagnostic criteria for the diagnosis rheumatoid arthritis, or the diagnostic criteria by Moll and Wright for the diagnosis psoriatic arthritis, or the modified New York diagnostic criteria for ankylosing spondylitis.
Clinical indication for starting treatment with methotrexate, TNFalpha- inhibitor or combination therapy.
Use of reliable method of contraception for women with childbearing potential.
You may not be if
Lack of cooperativity
Positive serology for hepatitis B or C
History of positive HIV status.
History of tuberculosis or untreated tuberculosis.
PPD more than 15 mm in previously BCG immunized subjects. PPD 6 mm or more if not previously BCG immunized.
Histoplasmosis or Listeriosis
Persistent or recurrent infections
Any inflammatory disease of permanence not related to RA, PSA or AS.
Pregnancy or breast-feeding.
Use of prednisolone more than 10 mg daily for 2 weeks at inclusion.
Use of TNFalpha-inhibitor the last 4 weeks.
History of cancer.
Uncontrolled diabetes.
Congestive heart failure (Nyha 3-4)
Recent stroke (within 3 months)
Previous diagnosis or signs of central nervous system demyelinating disease.
