Collecting and Storing Biological Samples From Patients With Ewing Sarcoma

OBJECTIVES: I. Collect biological specimens, including associated demographic and clinical data, from patients with Ewing sarcoma. II. Provide a repository for long-term storage of Ewing sarcoma-related biological materials. III. Make collected specimens available to qualified researchers to understand the biology of Ewing sarcoma and correlate these results with demographic and clinical data. OUTLINE: This is a multicenter study. Patients undergo collection of tumor specimens, bone marrow, and peripheral blood at diagnosis. Associated demographic and clinical data are collected and archived. Patients who are not enrolled on a therapeutic clinical trial are followed annually.