Proteases in Patients With Prostate Cancer That Has Spread to the Bone

You may be eligible if

• DISEASE CHARACTERISTICS:
• Meets 1 of the following criteria:
• * Diagnosis of metastatic prostate cancer
• * Patients with documented bone metastases on radiologic imaging studies must undergo bone marrow biopsy
• * Male patients ≥ 50 years of age without cancer who are scheduled to undergo bone biopsy for other clinically indicated reasons, including any of the following:
• * Myelodysplasia
• * Anemia
• * Monoclonal gammopathy of undetermined significance
• * Male or female patients ≥ 40 years of age without metastatic bone cancer who are scheduled to undergo an orthopedic procedure involving removal of bone specimen
• PATIENT CHARACTERISTICS:
• See Disease Characteristics
• PRIOR CONCURRENT THERAPY:
• Not specified