Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Minneapolis Heart Institute Foundation
With
Forest Laboratories
Patients who have been prescribed standard beta blockers but were unable to tolerate them due to side effects will be studied. They will take a new beta blocker, Nebivolol (Bystolic) for 30 days, if tolerated. Side effects will be tracked and compared to previous.
Age
21–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age ≥ 21
Male or female who is post-menopausal or not pregnant and using an approved contraceptive regimen
Previous beta blocker use and intolerant of beta blocker
You may not be if
Systolic blood pressure \< 100 mmHg unless another blood pressure medication is stopped at the time of study entry
Hospitalized for heart failure within the past 4 weeks
Bradycardia with a heart rate \< 60
Heart block greater than first degree
History of sick sinus syndrome (unless a permanent pacemaker is in place)
History of severe hepatic or renal dysfunction; serum Creatinine \> 2.0 or Amylase \> 3x normal
Use of CYP2D6 inhibitors (quinidine, propafenone, fluoxetine, paroxetine, etc.)
Ingestion of investigational drug within the past 30 days
Clareo Health | Alternative in Beta Blocker Intolerance: The ABBI Trial
