Premenopausal women

DSM-IV diagnosis of Dementia History of stroke

Immunocompromised

Active peptic ulcer, GI bleed, chronic inflammatory bowel disease, chronic diarrhea or past GI surgery that would impact drug absorption

Unstable Vitamin B-12 deficiency

Hematologic or solid malignancy within 5 years

Geriatric Depression Scale ≥ 6

Unstable medical condition

Alcohol or drug abuse history with 12-months of study entry

Significant drug allergy

Prisoners, compulsory psychiatric patients, or residents of nursing home or skilled nursing facility at entry

Any other experimental therapy with 30-days of study entry

A Multicenter, Double Blind, Placebo-Controlled, Safety and Tolerability Study of BMS-708163 in Patients With Prodromal Alzheimer's Disease