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Keep this study
Lead
United Therapeutics
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
A subject is eligible for inclusion in this study if all of the following criteria apply:
Between 18 and 75 years of age, inclusive.
Body weight at least 40 kg (approximately 90 lbs.)
PAH that is either idiopathic/heritable; associated with appetite suppressant or toxin use; associated with collagen vascular disease; associated with repaired congenital shunts; associated with HIV.
Currently receiving an approved endothelin receptor antagonist and/or an approved phosphodiesterase-5 inhibitor for at least 90 days and on a stable dose for at least the last 30 days.
Baseline six-minute walk distance (6MWD) between 150-425 meters
Previous testing (e.g., right heart catheterization, echocardiography) consistent with the diagnosis of PAH.
Reliable and cooperative with protocol requirements.
