A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023)
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Merck Sharp & Dohme LLC
Age
65–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Patient Specific:
Female is not of reproductive potential
Male who has a female partner(s) of child bearing potential, agrees to use acceptable method of contraception during the study
Has at least 10 years of education or work history
Has been a nonsmoker or has not used nicotine for at least 6 months
Has a diagnosis of mild-to-moderate Alzheimer's Disease
Has a reliable caregiver who consents to accompany the patient to all clinic visits, provide information to the study staff, and return for follow-up visits and procedures
Healthy Elderly Volunteer Specific:
Is in good general health
Has no clinically significant abnormality on electrocardiogram (ECG)
You may not be if
Participant Specific:
Has a history of a neurological disorder other than Alzheimer's disease
Is living in a nursing home
Has a history of stroke
Has a history of psychotic disorder, an active major depressive disorder, or history of schizophrenia
Has a history of a sleep disorder
Has a history of a cardiovascular disorder
Has a history of malignancy
Is participating or has participated in a study with an investigational compound, device, or vaccine for Alzheimer's disease
Consumes greater than 6 servings of caffeine (coffee, tea or cola etc.) per day
Consumes greater than 3 alcoholic beverages per day
Has had major surgery, donated or loss blood in past 8 weeks
Healthy Elderly Volunteer Specific:
Is mentally or legally incapacitated, has significant emotional problems, or has a history of a psychiatric disorder over the last 5-10 years
