Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Hartmut Malluche, MD
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Aged 18 years or older;
Chronic maintenance dialysis of at least 3 months' duration;
Mental competence;
Willingness to participate in the study;
Calcidiol levels within normal range.
You may not be if
Pregnancy;
Systemic illnesses or organ diseases that may affect bone (except type 1 or type 2 diabetes mellitus);
Clinical condition that may limit study participation (e.g., unstable angina, respiratory distress, infections).
Chronic alcoholism and/or drug addiction;
Participation in a study of an investigational drug during the past 90 days;
Allergy to tetracycline.
Planning to move out of the area within 2 years of the study;
On active transplant list;
Treatment within last 6 months with drugs that may affect bone metabolism (except for treatment with calcitriol, vitamin D analogs and/or calcimimetics).
Calcidiol level below the normal range. The current routine clinical practice in our dialysis clinics is to check calcidiol status twice yearly and supplement with vitamin D according to serum calcidiol levels. It is therefore unlikely that a substantial number of patients will be excluded due to this exclusion criterion.
