Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Zimmer Biomet
The NexGen LPS-FLex Mobile Bearing Knee received FDA approval for commercial distribution in the US on December 10, 2007. The approval was in accordance with a "condition of approval" to perform a 10-year post approval study to evaluate the longer-term safety and effectiveness of the LPS-Flex Mobile Bearing Knee. The post approval study will consist of patients from the investigational device exemption study arm (Group 1) as well as patients who are eligible for a total knee replacement and have been chosen to receive the LPS-Flex Mobile Knee (Group 2). Group 1 will be followed from 4 years through a total of 10 years from the date of surgery. Group 2 will be followed from pre-op through a total of 5 years from the date of surgery.
Age
Any age
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Osteoarthritis
Primary and secondary traumatic arthritis
Avascular necrosis of the femoral condyle
Moderate varus, valgus, or flexion deformities (i.e. valgus/varus deformity of less than or equal to 15 degrees, fixed flexion deformity of less than or equal to 10 degrees)
You may not be if
Previous history of infection in the affected joint and/or local/systemic infection that may affect the prosthetic joint
Insufficient bone stock on femoral or tibial surfaces
Skeletal immaturity
Neuropathic arthropathy
Osteoporosis or any loss of musculature or neuromuscular disease that compromises the affected limb
A stable, painless arthrodesis in a satisfactory functional position
Severe instability secondary to the absence of collateral integrity
Total knee arthroplasty is contraindicated in patients who have rheumatoid arthritis (RA) and an ulcer of the skin or a history of recurrent breakdown of the skin because their risk of postoperative infection is greater. RA patient using steroids may also have increased risk of infection. Late infections in RA patients have been reported 24+ months postoperative.
Patient is a poor compliance risk, i.e., history of ethanol or drug abuse, or mental handicap that would compromise patient compliance with respect to rehabilitation or follow-up
Patient is not willing or able to give informed consent to participate in the follow-up program
Patient is not willing to return for all scheduled follow-up appointments as defined by this protocol.
Clareo Health | Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee
