Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Transonic Systems Inc.
With
National Heart, Lung, and Blood Institute (NHLBI)
Age
0–18
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age: less than 18 years.
Admission to the CICU (Cardiac Intensive Care Unit) (8S) or MISICU (Medical-Surgical Intensive Care Unit) (7S) of the Children's Hospital Boston.
Presence of a central venous catheter with its tip in the superior vena cava or a catheter in the pulmonary artery, documented by radiography.
Requirement for mechanical ventilation via an endotracheal or tracheostomy tube.
Presence of an arterial catheter.
Patients must have a two ventricle circulation.
You may not be if
Endotracheal tube leak of greater than 10%.
A significant air leak around the endotracheal tube makes VO2 impossible to measure.
Presence of relevant intracardiac shunt.
Intracardiac shunt will decrease the area under the arterial dilution curve unpredictably, making cardiac index calculations unreliable.
A patent foramen ovale and a single ventricular septal defect less than or equal to 2mm or an atrial septal defect less than or equal to 3mm will be considered irrelevant for the purposes of this study.
Previous enrollment in an incompatible research study.
Current or prior diagnosis of heparin induced thrombocytopenia.
A small amount of heparin is required to flush the extracorporeal AV (Arteriovenous) loop that is required for the measurements.
Pneumothorax with ongoing air leak.
An air leak will invalidate the measurement of VO2.
